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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADRA2A
All Species:
8.79
Human Site:
T344
Identified Species:
17.58
UniProt:
P08913
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P08913
NP_000672.3
450
48957
T344
P
G
A
T
G
I
G
T
P
A
A
G
P
G
E
Chimpanzee
Pan troglodytes
XP_521603
468
50335
T328
P
G
A
T
G
I
G
T
P
A
A
G
P
G
E
Rhesus Macaque
Macaca mulatta
XP_001087738
450
49113
T344
L
G
E
T
G
I
G
T
A
A
A
G
P
G
V
Dog
Lupus familis
XP_544018
622
67080
G362
R
G
A
A
G
P
G
G
A
G
G
G
A
G
P
Cat
Felis silvestris
Mouse
Mus musculus
Q01338
450
48847
A344
P
G
A
A
G
P
G
A
S
G
S
G
H
G
E
Rat
Rattus norvegicus
P22909
450
48921
A344
P
G
A
A
G
P
G
A
S
G
S
G
Q
G
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513049
394
43582
L310
S
D
P
A
S
L
T
L
R
R
H
R
G
G
W
Chicken
Gallus gallus
XP_426355
614
69002
F508
S
N
R
S
M
E
F
F
S
Y
R
R
R
R
K
Frog
Xenopus laevis
P24628
442
49720
P336
H
P
K
D
S
T
K
P
A
K
V
F
E
I
Q
Zebra Danio
Brachydanio rerio
Q90WY4
388
43978
N304
S
R
W
K
G
R
Q
N
R
E
K
R
F
T
F
Tiger Blowfish
Takifugu rubipres
P53453
463
52101
T352
T
E
K
N
G
D
P
T
K
E
A
Q
G
N
P
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001200819
471
53401
L356
M
R
A
S
D
T
H
L
R
P
D
T
P
Q
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.6
96.4
58.5
N.A.
92.2
90.8
N.A.
45.5
43
33.3
60.4
32.6
N.A.
N.A.
N.A.
36
Protein Similarity:
100
86.1
96.6
62
N.A.
94
92.8
N.A.
53.1
51.2
50.6
70.6
49.4
N.A.
N.A.
N.A.
53
P-Site Identity:
100
100
73.3
40
N.A.
53.3
53.3
N.A.
6.6
0
0
6.6
20
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
73.3
40
N.A.
60
60
N.A.
13.3
13.3
6.6
6.6
20
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
50
34
0
0
0
17
25
25
34
0
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
9
9
9
0
0
0
0
9
0
0
0
0
% D
% Glu:
0
9
9
0
0
9
0
0
0
17
0
0
9
0
34
% E
% Phe:
0
0
0
0
0
0
9
9
0
0
0
9
9
0
9
% F
% Gly:
0
50
0
0
67
0
50
9
0
25
9
50
17
59
0
% G
% His:
9
0
0
0
0
0
9
0
0
0
9
0
9
0
0
% H
% Ile:
0
0
0
0
0
25
0
0
0
0
0
0
0
9
0
% I
% Lys:
0
0
17
9
0
0
9
0
9
9
9
0
0
0
9
% K
% Leu:
9
0
0
0
0
9
0
17
0
0
0
0
0
0
0
% L
% Met:
9
0
0
0
9
0
0
0
0
0
0
0
0
0
9
% M
% Asn:
0
9
0
9
0
0
0
9
0
0
0
0
0
9
0
% N
% Pro:
34
9
9
0
0
25
9
9
17
9
0
0
34
0
17
% P
% Gln:
0
0
0
0
0
0
9
0
0
0
0
9
9
9
9
% Q
% Arg:
9
17
9
0
0
9
0
0
25
9
9
25
9
9
0
% R
% Ser:
25
0
0
17
17
0
0
0
25
0
17
0
0
0
0
% S
% Thr:
9
0
0
25
0
17
9
34
0
0
0
9
0
9
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
9
% V
% Trp:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
9
% W
% Tyr:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _